Project
We are looking for talented PhD candidates who are interested to develop a new biosensor technology for continuous biomolecular sensing based on particle motion, for applications in biological processes and healthcare. Important topics are the development of sensor chemistries and fluidics, insights into critical parameters for sensor performance, and validation of the sensor with realistic biological systems and closed-loop process control.
Candidates should have a background in engineering and/or analytical sciences, e.g. chemical engineering, physical engineering, biophysics, analytical chemistry.
The project will be performed in collaboration with Eindhoven University of Technology and with partners in the CONSENSE European project https://cordis.europa.eu/project/id/955623
Publications
Recent publications of our research work are:
‘Continuous biomarker monitoring by particle mobility sensing with single molecule resolution’, Nature Communications (2018) https://www.nature.com/articles/s41467-018-04802-8
‘Multiplexed continuous biosensing by single-molecule encoded nanoswitches’, Nano Letters (2020) https://pubs.acs.org/doi/abs/10.1021/acs.nanolett.9b04561
‘Continuous small-molecule monitoring with a digital single particle switch’, ACS Sensors (2020) https://pubs.acs.org/doi/10.1021/acssensors.0c00220
Conditions of employment
We offer:
A challenging job in an enthusiastic multidisciplinary team.
An appointment (1 fte) as junior researcher in Helia Biomonitoring. Starting date: flexible, preferably 1 March 2021.
Access to the courses of the PhD program of Eindhoven University of Technology.
Gross monthly salary in accordance with the Collective Labour Agreement of the Dutch Universities (CAO NU), including a holiday allowance and an end of year allowance.
Information and application
More information can be obtained from Prof. M.W.J. Prins, m.w.j.prins@tue.nl.
Application
Your application can be sent to prof. M.W.J. Prins. Applications must include all of the following: (i) a personal motivation letter, (ii) a Curriculum Vitae including the names and contact details of at least two references, (iii) lists of courses and grades of your BSc and MSc degrees, as originals and as transcripts, (iv) your final BSc thesis and your final MSc thesis
Only complete applications will be considered. Screening of applicants will start as soon as applications are received and will continue until the position has been filled.