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Fundamental principles of the BPM technology


Continuous biomarker monitoring with single molecule resolution by measuring free particle motion

2022 | Nature Communications

Continuous small-molecule monitoring with a digital single particle switch

2020 | ACS Sensors 

Continuous biomarker monitoring by particle mobility sensing with single molecule resolution

2018 | Nature Communications 

Publications related to the BPM technology

Towards continuous monitoring of TNF-α at picomolar concentrations using biosensing by particle motion

2024 | Biosensors and Bioelectronics

Sandwich immunosensor based on particle motion: how do reactant concentrations and reaction pathways determine the time-dependent response of the sensor?

2023 | ACS Sensors

Integrated sampling-and-sensing using microdialysis and Biosensing by Particle Motion for continuous cortisol monitoring

2023 | Sensors & Diagnostics

Real-time continuous monitoring of dynamic concentration profiles studied with biosensing by particle motion

2023 | Lab on a Chip

High-throughput single-molecule sensors: how can the signals be analyzed in real time for achieving real-time continuous biosensing?

2023 | ACS Sensors

Real-time immunosensor for small molecule monitoring in industrial food processes

2023 | Analytical Chemistry

Reversible immunosensor for the continuous monitoring of cortisol in blood plasma sampled with microdialysis

2022 | ACS Sensors

Real-time monitoring of biomolecules: dynamic response limits of affinity-based sensors

2022 | ACS Sensors

Sensing methodology for the rapid monitoring of biomolecules at low concentrations over long time spans

2021 | ACS Sensors

Real-time detection of state transitions in stochastic signals from biological systems

2021 | ACS Omega

Click-coupling to electrostatically-grafted polymers greatly improves the stability of a continuous monitoring sensor with single-molecule resolution

2021 | ACS Sensors

How reactivity variability of biofunctionalized particles is determined by superpositional heterogeneities

2021 | ACS Nano

Multiplexed continuous biosensing by single-molecule encoded nanoswitches

2020 | Nano Letters

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