Fundamental principles of the BPM technology

 

Continuous biomarker monitoring with single molecule resolution by measuring free particle motion

2022 | Nature Communications

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Continuous small-molecule monitoring with a digital single particle switch

2020 | ACS Sensors 

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Continuous biomarker monitoring by particle mobility sensing with single molecule resolution

2018 | Nature Communications 

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Publications related to the BPM technology

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Continuous protein sensing using fast-dissociating antibody fragments in competition-based biosensing by particle motion

2025 | ACS Sensors

 

How highly heterogeneous sensors with single-molecule resolution can result in robust continuous monitoring over long time spans

2024 | Advanced Science

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Revealing spatial molecular heterogeneity of high-density biofunctionalized surfaces using DNA-PAINT

2024 | ACS Applied Materials & Interfaces

 

Continuous biosensor based on particle motion: how does the concentration measurement precision depend on time scale

2024 | ACS Sensors

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Oriented antibody coupling to an antifouling polymer using glycan remodeling for biosensing by particle motion

2024 | Bioconjugate Chemistry

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Molecular origins of long-term changes in a competitive continuous biosensor with single-molecule resolution

2024 | ACS Sensors

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Towards continuous monitoring of TNF-α at picomolar concentrations using biosensing by particle motion

2024 | Biosensors and Bioelectronics

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Sandwich immunosensor based on particle motion: how do reactant concentrations and reaction pathways determine the time-dependent response of the sensor?

2023 | ACS Sensors

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Integrated sampling-and-sensing using microdialysis and Biosensing by Particle Motion for continuous cortisol monitoring

2023 | Sensors & Diagnostics

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Real-time continuous monitoring of dynamic concentration profiles studied with biosensing by particle motion

2023 | Lab on a Chip

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High-throughput single-molecule sensors: how can the signals be analyzed in real time for achieving real-time continuous biosensing?

2023 | ACS Sensors

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Real-time immunosensor for small molecule monitoring in industrial food processes

2023 | Analytical Chemistry

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Reversible immunosensor for the continuous monitoring of cortisol in blood plasma sampled with microdialysis

2022 | ACS Sensors

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Real-time monitoring of biomolecules: dynamic response limits of affinity-based sensors

2022 | ACS Sensors

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Sensing methodology for the rapid monitoring of biomolecules at low concentrations over long time spans

2021 | ACS Sensors

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Real-time detection of state transitions in stochastic signals from biological systems

2021 | ACS Omega

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Click-coupling to electrostatically-grafted polymers greatly improves the stability of a continuous monitoring sensor with single-molecule resolution

2021 | ACS Sensors

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How reactivity variability of biofunctionalized particles is determined by superpositional heterogeneities

2021 | ACS Nano

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Multiplexed continuous biosensing by single-molecule encoded nanoswitches

2020 | Nano Letters